AI Summary1. Run InterProScan for domain/family annotation. 2. Run eggnog-mapper for orthology-based annotation. 3. Run DIAMOND and resolve taxonomy with TaxonKit.
Install
Copy this and paste it into Claude Code, Cursor, or any AI assistant:
I want to install the "bio-annotation" skill in my project. Please run this command in my terminal: # Install skill into your project (2 files) mkdir -p .claude/skills/bio-annotation && curl --retry 3 --retry-delay 2 --retry-all-errors -o .claude/skills/bio-annotation/SKILL.md "https://raw.githubusercontent.com/majiayu000/claude-skill-registry/main/skills/domains/bio-annotation/SKILL.md" && curl --retry 3 --retry-delay 2 --retry-all-errors -o .claude/skills/bio-annotation/metadata.json "https://raw.githubusercontent.com/majiayu000/claude-skill-registry/main/skills/domains/bio-annotation/metadata.json" Then restart Claude Code (or reload the window in Cursor) so the skill is picked up.
Description
Functional annotation and taxonomy inference from sequence homology.
Prerequisites
• Tools installed via pixi (see pixi.toml). • Reference DB root: /media/shared-expansion/db/ (wsu; override per machine branch). • Input FASTA and reference DBs are readable.
Tools
• interproscan v6.0.0 • eggnog-mapper v2.1.13 • diamond v2.1.16 • taxonkit v0.20.0
When to use
• Functional annotation and taxonomy inference from sequence homology.
Inputs
• proteins.faa (FASTA protein sequences). • reference_db/ (eggNOG, InterPro, DIAMOND databases + taxdump).
Discussion
Health Signals
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